Nanoscale science and technology, where length scale comparable to atoms and molecules modify and control macroscopic properties of solids through quantum effect, are presented. As the size approaches the nanoscale level, dimensions play a critical role and many distinctive and potentially useful phenomena and properties emerge. The lectures include physics at nanoscale, fabrication of nanostructured materials and technology of devices using nanostructures as well as modefication of optical, electric, magnetic and chemical properties. The speakers will also present fundamental size-dependent phenomena and new capabilities to develop applications to semiconductor, optical devices and phononic crystals.